8-methoxy-N-propyl-1,2,3,4-tetrahydronaphthalen-2-amine → HCID 67250174, compound

Participants

Reaction Steps

Synthesis works according to the preparation of A4-1 or A4-4 when using N-(8-methoxytetralin-2-yl)-N-propylamine (A2-1: R═OMe) and 2-pyrazolo[1,5-a]pyridinyl acetic acid (A3-12: R═OMe, Cy=2-pyrazolo[1,5-a]pyridinyl) (synthesis according to literature: Awano, K. Chem Pharm Bull 1992, Vol 40, p 631; Löber, S Bioorg Med Chem Lett 2002, Vol 12, p 2377) and subsequent reaction according to the synthesis of A5-1.

Provenance & Evidence