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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2042796Generated: November 3, 2026

Pivaloyl chloride → N-(3-amino-4-chloro-2-fluorobenzyl)pivalamide

https://huagongshe.com/reaction/2042796

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPivaloyl chlorideHCID 62493—
ReactantHCID 56839970HCID 56839970—
ProductN-(3-amino-4-chloro-2-fluorobenzyl)pivalamideHCID 5683997836%

Reaction Steps

The sub-title compound is prepared from crude 3-amino-4-chloro-2-fluoro-benzylamine, 2,2-dimethyl-propionic acid chloride and TEA in analogy to step Ae.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586604B2
Source datasetuspto-grants-2013_11
ORD IDord-6a8f6d3812be452b9fb4afbd80ba260d
Source noteuspto-grants-2013_11