HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(3-Nitro-2,4-dimethyl-benzyl)-2,2-dimethyl-propionamide → N-(3-Amino-2,4-dimethyl-benzyl)-2,2-dimethyl-propionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(3-Nitro-2,4-dimethyl-benzyl)-2,2-dimethyl-propionamide | HCID 68032644 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-(3-Amino-2,4-dimethyl-benzyl)-2,2-dimethyl-propionamide | HCID 56839979 | — |
Reaction Steps
A mixture of N-(3-nitro-2,4-dimethyl-benzyl)-2,2-dimethyl-propionamide (500 mg, 1.89 mmol), Pd/C (50 mg) and MeOH (20 mL) is stirred for 9 h under a hydrogen atmosphere (50 psi). The catalyst is removed by filtration and the filtrate is concentrated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586604B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-109b03cc4a7f4183bf58de1d17fa17ad |
| Source note | uspto-grants-2013_11 |