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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2042821Generated: October 29, 2026

Nitric Acid → HCID 178496181, compound

https://huagongshe.com/reaction/2042821

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNitric AcidHCID 944—
ReactantHCID 178496180HCID 178496180—
SolventSulfuric AcidHCID 1118—
ProductHCID 178496181HCID 178496181—

Reaction Steps

The sub-title compound is prepared from 6-chloro-2-(2-methoxy-ethoxy)-N-(trans-4-trifluoromethyl-cyclohexyl)-nicotinamide (2.20 g, 5.78 mmol), fuming HNO3 (5 mL) and conc. H2SO4 (10 mL) in analogy to example 1c.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586604B2
Source datasetuspto-grants-2013_11
ORD IDord-3e770a5852c2492994eea3b4e9770be0
Source noteuspto-grants-2013_11