HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylcarbodiimide → HCID 178481227, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylcarbodiimide | HCID 12734 | — |
| Reactant | N-(2,4-Difluoro-3-isothiocyanato-benzyl)-2,2-dimethyl-propionamide | HCID 56840193 | — |
| Reactant | HCID 178482445 | HCID 178482445 | — |
| Product | HCID 178481227 | HCID 178481227 | — |
Reaction Steps
The title compound is prepared from N-(2,4-difluoro-3-isothiocyanato-benzyl)-2,2-dimethyl-propionamide (150 mg, 0.38 mmol) and 5-amino-2-(2,2-difluoro-ethoxy)-N-(trans-4-trifluoromethyl-cyclohexyl)-6-methylamino-nicotinamide (150 mg, 0.38 mmol) with DIC in analogy to examples 8a/8b.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586604B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-2fc48ca6c6054fb59c7732c4de67cb74 |
| Source note | uspto-grants-2013_11 |