HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-morpholin-4-ylmethyl-6-nitro-N-phenyl-benzamide → 2-amino-6-(4-morpholinylmethyl)-N-phenylBenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-morpholin-4-ylmethyl-6-nitro-N-phenyl-benzamide | HCID 59841084 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-amino-6-(4-morpholinylmethyl)-N-phenylBenzamide | HCID 59841062 | — |
Reaction Steps
A solution of compound 7 (0.3 g) and 10% Pd/C (30 mg) in methanol (35 mL) was stirred under hydrogen (1 atm) for 1.5 h. The mixture was filtered through a bed of CELITE® and the filtrate was concentrated to provide a yellow solid product, intermediate compound 2. ESI-MS m/z=312 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586597B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-e9a8afdaa046413caa931f2c81433aa7 |
| Source note | uspto-grants-2013_11 |