Acetic Acid → HCID 53325317, compound

Participants

Reaction Steps

To a solution of the peracetylate 59 (208 mg, 0.35 mmol) in MeOH (10 mL) was added NaOMe (25 wt. % in MeOH, 0.2 mL). The reaction mixture was stirred at ambient temperature for 3 h. Acetic acid was added to neutralize the reaction mixture and concentrated in vacuo. The residue was redissolved in MeOH and further purified by prep HPLC (C18) to provide the titled compound (106 mg, 71 mmol) as a white solid.

Provenance & Evidence