反应详情

To a solution of compound 82 (13 g, 47.9 mmol) in methylene chloride (100 mL) at 0° C. was added bromine (2.7 mL, 52.7 mmol) dropwise. After reaction complete, the resulting solution was evaporated under reduced pressure. The residue was quenched with saturated Na2S2O4 solution, work-up with Et2O. After evaporation of volatile solvent, the title compound was obtained by trituration with hexane.

1. customAfter reaction complete
2. customthe resulting solution was evaporated under reduced pressure
3. customThe residue was quenched with saturated Na2S2O4 solution, work-up with Et2O
4. customAfter evaporation of volatile solvent