Water → HCID 86680891, compound

Participants

Reaction Steps

The solution of alcohol 89 (1.0 g, 2.28 mmol) and p-toluenesulfonyl chloride (2.3 g, 11.8 mmol) in 2,6-lutidine (22.8 mL) was stirred at room temperature for 15 h. H2O (150 mL) was added to the reaction mixture and then extracted with EtOAc. The organic layer was dried over anhydrous MgSO4, filtered and concentrated in vacuo. Purification by silica gel column chromatography provided desired toluenesulfonate 90 (1.03 g, 78%) as a solid.

Provenance & Evidence