Sodium Methoxide → HCID 53318599, compound

Participants

Reaction Steps

The solution of toluenesulfonate 90 (104 mg, 0.18 mmol) and NaOMe (25 wt. % in MeOH, 5 mL) in methanol (3.5 mL) was stirred at room temperature for 15 h. After reaction complete, the resulting solution was quenched with H2O. Reaction mixture was evaporated under reduced pressure. The residue was purified by prep HPLC (C18) to afford the titled compound 91 (12 mg, 56%) as a solid.

Provenance & Evidence