Triethylamine → HCID 53323798, compound

Participants

Reaction Steps

The solution of toluenesulfonate 90 (612 mg, 1.03 mmol), tetrazole (0.45 M in acetonitrile) (11.5 mL 5.17 mmol) and triethyl amine (0.72 mL 5.17 mmol) in DMF (2.0 mL) was stirred at 80° C. for 3 d. Reaction mixture was evaporated under reduced pressure. The residue was purified by prep HPLC (C18) to afford the titled compound 98 (120 mg, 24%) as a solid.

Provenance & Evidence