Benzocaine → HCID 16228385, compound

HRID 2043098Notes

Reaction equation

HRID 2043098 reaction equation
C([O:3][C:4](=[O:12])[C:5]1[CH:10]=[CH:9][C:8]([NH2:11])=[CH:7][CH:6]=1)C.[CH:13]1([C:18](O)=[O:19])[CH2:17][CH2:16][CH2:15][CH2:14]1.[OH-].[Na+]>C(O)C>[CH:13]1([C:18]([NH:11][C:8]2[CH:7]=[CH:6][C:5]([C:4]([OH:3])=[O:12])=[CH:10][CH:9]=2)=[O:19])[CH2:17][CH2:16][CH2:15][CH2:14]1

Participants

5

Reactant 3

HCID 2337BenzocaineHCID 14798Sodium HydroxideHCID 18840Cyclopentanecarboxylic acid

Product 1

HCID 16228385HCID 16228385, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4-Aminobenzoic acid ethyl ester was reacted with cyclopentanecarboxylic acid by method E, and the resulting ester was hydrolyzed by boiling with sodium hydroxide in aqueous ethanol. The product with the molecular weight of 233.27 (C13H15NO3); MS (ESI): 234 (M+H+) was obtained in this way.

Workup

  1. customMS (ESI): 234 (M+H+) was obtained in this way

Sources & evidence

ORD record
ord-4edfdc77259f4a488706bdcdb497a5ef
Source dataset
uspto-grants-2013_11
Patent number
US08586609B2

Reaction notes

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