4-Nitrophenol → HCID 178510998, compound

Participants

Reaction Steps

To a magnetically stirred solution of HO-GlyLys [ε-CBz] [α-Lys] [Boc]2 (430 mg, 0.65 mmol) and EtOAc (10 ml) was added, in the following order, p-nitrophenol (99 mg, 0.71 mmol) and DCC (147 mg, 0.71 mmol). The reaction and product isolation were carried out according to the method described in Example 19.vi Silica gel flash chromatography (EtOAc) provided PNPO-GlyLys [ε-CBz] [α-Lys] [Boc]2 (Rf 0.4) (344 mg, 66%) as an off white solid.

Provenance & Evidence