HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → N-[(4s)-1-Azatricyclo[3.3.1.13,7]dec-4-yl]-2,4-dichlorobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 2,4-Dichlorobenzoic Acid | HCID 5787 | — |
| Reactant | 1-Azatricyclo[3.3.1.1,3,7]decan-4-amine | HCID 15686618 | — |
| Product | N-[(4s)-1-Azatricyclo[3.3.1.13,7]dec-4-yl]-2,4-dichlorobenzamide | HCID 16067942 | — |
Reaction Steps
Prepared from (4s)-1-azatricyclo[3.3.1.13,7]dec-4-ylamine and 2,4-dichlorobenzoic acid (Aldrich) according to method B; 1H NMR (500 MHz, methanol-d4) δ 1.91-1.99 (m, 3H), 2.04 (s, 1H), 2.21-2.33 (m, 4H), 3.44 (s, 2H), 3.55 (s, 4H), 4.41 (s, 1H), 7.41-7.49 (m, 2H), 7.54-7.59 (m, 1H); MS (APCI/NH3) m/z 325 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586746B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-22da48031f604cb79c0a42bb752e4c18 |
| Source note | uspto-grants-2013_11 |