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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2043880Generated: November 1, 2026

Isoamylamine → {2-[3-Cyclohexyl-3-(2,2-dimethyl-propyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid

https://huagongshe.com/reaction/2043880

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsoamylamineHCID 7894—
ReactantCyclohexanoneHCID 7967—
Reactant[2-(3-Cyclohexyl-3-phenethylureido)-thiazol-5-ylsulfanyl]-acetic acidHCID 11993791—
SolventEthyl AcetateHCID 8857—
Product{2-[3-Cyclohexyl-3-(2,2-dimethyl-propyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acidHCID 16101129—

Reaction Steps

Prepared as described for the synthesis of [2-(3-cyclohexyl-3-phenethyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid, from 3,3-dimethyl-propylamine, cyclohexanone and 2-amino-thiazol-5-ylsulfanyl)-acetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586614B2
Source datasetuspto-grants-2013_11
ORD IDord-535cf99fcfc044f581258e2e6780b9e0
Source noteuspto-grants-2013_11