Ethyl Propionate → HCID 16101135, compound

HRID 2043887Notes

Reaction equation

[CH:1]1([N:7]([CH2:21][CH2:22][C:23]2[CH:28]=CC=CC=2)[C:8](=[O:20])[NH:9][C:10]2[S:11][C:12]([S:15][CH2:16][C:17](O)=O)=[CH:13][N:14]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C(N)CCC.C1(=O)CCCCC1.C([O:43][C:44](=[O:47])CC)C>>[CH2:21]([N:7]([CH:1]1[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1)[C:8](=[O:20])[NH:9][C:10]1[S:11][C:12]([S:15][CH2:16][CH2:17][C:44]([OH:47])=[O:43])=[CH:13][N:14]=1)[CH2:22][CH2:23][CH3:28]

Participants

Reactant 4

HCID 7749Ethyl Propionate

HCID 7967Cyclohexanone

HCID 8007Butylamine

HCID 11993791[2-(3-Cyclohexyl-3-phenethylureido)-thiazol-5-ylsulfanyl]-acetic acid

Product 1

HCID 16101135HCID 16101135, compound

Procedure

Prepared as described for the synthesis of [2-(3-cyclohexyl-3-phenethyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid, from n-butylamine, cyclohexanone and 2-amino-thiazol-5-ylsulfanyl)propionic acid ethyl ester.

Workup

customPrepared

Sources & evidence

ORD record: ord-1b3c2c40f8764e2cbafbfd757c05235b
Source dataset: uspto-grants-2013_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08586614B2

Reaction notes

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