Butylamine → HCID 57668238, compound

HRID 2043914Notes

Reaction equation

HRID 2043914 reaction equation
[CH:1]1([N:7]([CH2:21][CH2:22][C:23]2[CH:28]=CC=C[CH:24]=2)[C:8](=[O:20])[NH:9][C:10]2[S:11][C:12]([S:15][CH2:16][C:17](O)=O)=[CH:13][N:14]=2)[CH2:6][CH2:5][CH2:4]CC1.C(=O)CC(C)C.C(N)CCC.C([O:42][C:43](=[O:53])C(SC1SC(N)=NC=1)C)C>>[CH2:1]([N:7]([CH2:21][CH2:22][CH:23]([CH3:24])[CH3:28])[C:8](=[O:20])[NH:9][C:10]1[S:11][C:12]([S:15][CH2:16][CH2:17][C:43]([OH:53])=[O:42])=[CH:13][N:14]=1)[CH2:6][CH2:5][CH3:4]

Participants

5

Reactant 4

HCID 8007ButylamineHCID 115523-MethylbutanalHCID 11993791[2-(3-Cyclohexyl-3-phenethylureido)-thiazol-5-ylsulfanyl]-acetic acidHCID 86610213(2-Aminothiazole-5-ylsulfanyl)-propionic acid ethyl ester

Product 1

HCID 57668238HCID 57668238, compound

Procedure

Prepared as described for the synthesis of [2-(3-cyclohexyl-3-phenethyl-ureido)-thiazol-5-ylsulfanyl]-acetic acid using isovaleraldehyde, butylamine and (2-amino-thiazol-5-ylsulfanyl)-propionic acid ethyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-9b5b3443980c48e9b9ce313b39a3613e
Source dataset
uspto-grants-2013_11
Patent number
US08586614B2

Reaction notes

Loading…