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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2043953Generated: October 29, 2026

Ethyl 2-(2-aminothiazol-5-ylthio)acetate → HCID 58206873, compound

https://huagongshe.com/reaction/2043953

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(2-aminothiazol-5-ylthio)acetateHCID 21455623—
Reactant{2-[3-Cyclopentylmethyl-3-(4-methanesulfonyl-phenyl)-ureido]thiazol-4-yl}-acetic acidHCID 57668194—
ReactantN-(Cyclopentylmethyl)-3-(trifluoromethoxy)anilineHCID 61343184—
ReactantHCID 86629902HCID 86629902—
ProductHCID 58206873HCID 58206873—

Reaction Steps

The title compound was prepared via {2-[3-cyclopentylmethyl-3-(3-trifluoromethoxy-phenyl)ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester in a similar manner as described for the synthesis of {2-[3-cyclopentylmethyl-3-(4-methanesulfonyl-phenyl)-ureido]-thiazol-4-yl}-acetic acid, using cyclopentylmethyl-(3-trifluoromethoxy-phenyl)-amine and (2-amino-thiazol-5-ylsulfanyl)acetic acid ethyl ester

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586614B2
Source datasetuspto-grants-2013_11
ORD IDord-f24dabea31f74ac794fbed1ef55aab91
Source noteuspto-grants-2013_11