HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Aminoacetanilide → HCID 57668332, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Aminoacetanilide | HCID 7604 | — |
| Reactant | 3,3-Dimethylbutanal | HCID 76335 | — |
| Reactant | Ethyl 2-(2-aminothiazol-5-ylthio)acetate | HCID 21455623 | — |
| Reactant | {2-[3-Cyclopentylmethyl-3-(3,4-difluoro-phenyl)-ureido]-thiazol-4-yl}-acetic acid | HCID 57668246 | — |
| Reactant | HCID 86629910 | HCID 86629910 | — |
| Product | HCID 57668332 | HCID 57668332 | — |
Reaction Steps
The title compound was prepared via {2-[3-(3-acetylamino-phenyl)-3-(3,3-dimethyl-butyl)ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester in a similar manner as described for the synthesis of {2-[3-cyclopentylmethyl-3-(3,4-difluoro-phenyl)-ureido]-thiazol-4-yl}-acetic acid, using N-(3-amino-phenyl)-acetamide, 3,3-dimethylbutyraldehyde and (2-amino-thiazol-5-ylsulfanyl)acetic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586614B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-5fb2ac7089494ad59e1e2f43ca0b2120 |
| Source note | uspto-grants-2013_11 |