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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2043963Generated: October 29, 2026

N-(Cyclohexylmethyl)-2H-1,3-benzodioxol-5-amine → HCID 57668436, compound

https://huagongshe.com/reaction/2043963

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(Cyclohexylmethyl)-2H-1,3-benzodioxol-5-amineHCID 18778581—
ReactantEthyl 2-(2-aminothiazol-5-ylthio)acetateHCID 21455623—
Reactant{2-[3-Cyclopentylmethyl-3-(4-methanesulfonyl-phenyl)-ureido]thiazol-4-yl}-acetic acidHCID 57668194—
ReactantHCID 86629912HCID 86629912—
ProductHCID 57668436HCID 57668436—

Reaction Steps

The title compound was prepared via [2-(3-benzo[1,3]dioxol-5-yl-3-cyclohexylmethyl-ureido)thiazol-5-ylsulfanyl]-acetic acid ethyl ester in a similar manner as described for the synthesis of {2-[3-cyclopentylmethyl-3-(4-methanesulfonyl-phenyl)-ureido]-thiazol-4-yl}-acetic acid, using benzo[1,3]dioxol-5-yl-cyclohexylmethyl-amine and (2-amino-thiazol-5-ylsulfanyl)acetic acid ethyl ester

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586614B2
Source datasetuspto-grants-2013_11
ORD IDord-f9e928f3cfee4e11a4dbc861f7c4a0bd
Source noteuspto-grants-2013_11