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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2043979Generated: October 29, 2026

Ethyl 2-(2-aminothiazol-5-ylthio)acetate → HCID 57668421, compound

https://huagongshe.com/reaction/2043979

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(2-aminothiazol-5-ylthio)acetateHCID 21455623—
Reactant{2-[3-Cyclopentylmethyl-3-(4-methanesulfonyl-phenyl)-ureido]thiazol-4-yl}-acetic acidHCID 57668194—
ReactantN-(2-Cyclopentylethyl)-3,4-difluoroanilineHCID 66961983—
ReactantHCID 86629928HCID 86629928—
ProductHCID 57668421HCID 57668421—

Reaction Steps

The title compound was prepared via {2-[3-cyclopentylethyl-3-(3,4-difluoro-phenyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester in a similar manner as described for the synthesis of {2-[3-cyclopentylmethyl-3-(4-methanesulfonyl-phenyl)-ureido]-thiazol-4-yl}-acetic acid, using cyclopentylethyl-(3,4-difluorophenyl)-amine and (2-amino-thiazol-5-ylsulfanyl)acetic acid ethyl ester

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08586614B2
Source datasetuspto-grants-2013_11
ORD IDord-16d281cd93314d0b86dede082c1fefba
Source noteuspto-grants-2013_11