HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 78023548, compound → HCID 71183145, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 78023548 | HCID 78023548 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 71183145 | HCID 71183145 | — |
Reaction Steps
A solution of 150 mg 3-(pyridin-2-ylmethylene)-6-(4-(trifluoromethoxy)phenyl)chroman-4-one (0.38 mmol) in 20 mL EtOH with catalytic Pd/C was stirred under 1 atm of hydrogen gas for 16 h. The reaction was filtered through celite and the filtrate concentrated. The filtrate was purified on silica gel column eluting with EA:Hex. 85 mg of an off-white solid was collected. m/z=400.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586732B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-b86d935305a3449b80d562a62a0ec176 |
| Source note | uspto-grants-2013_11 |