Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | HCID 23642285 | HCID 23642285 | — |
| Solvent | tert-Butyl methyl ether | HCID 15413 | — |
| Product | HCID 86633509 | HCID 86633509 | — |
Reaction Steps
A suspension of 600 mg 5-Methyl-2-(2′,4′-dichloro-3′-methylanilino)phenylacetic acid (1.85 mmoles) in 6 ml tert. Butyl methyl ether (TBME) is heated to 40° C. 137 mg diethylamine (1.85 mmoles) are dropwise added. The resulting slightly cloudy solution is clarified via hot filtration through a Whatman glasfiber filter. The filter is rinsed with 2 ml TBME of 40° C. The filtrate is allowed to cool slowly.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08586782B2 |
|---|
| Source dataset | uspto-grants-2013_11 |
|---|
| ORD ID | ord-32fc5dfcb38b4e799f93d1dc4b320c9c |
|---|
| Source note | uspto-grants-2013_11 |
|---|
