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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 204460Generated: October 31, 2026

Potassium Cation → 1-Oxo-2-(4-trifluoromethoxy-benzyl)-7-trifluoromethyl-2,3-dihydro-1H-isoindole-5-carbonitrile

https://huagongshe.com/reaction/204460

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CationHCID 813—
ReactantCyanideHCID 5975—
ReactantHexamethylphosphoramideHCID 12679—
Reactant5-Chloro-2-(4-trifluoromethoxy-benzyl)-7-trifluoromethyl-2,3-dihydro-isoindol-1-oneHCID 11682976—
ReactantHCID 178420554HCID 178420554—
Product1-Oxo-2-(4-trifluoromethoxy-benzyl)-7-trifluoromethyl-2,3-dihydro-1H-isoindole-5-carbonitrileHCID 86635672—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-c2c08ca090a34eafa6a11a0d27f416f3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)