HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Azide → (8-Methyl-2-o-tolylquinolin-3-yl)methanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | 3-(Chloromethyl)-8-methyl-2-o-tolylquinoline | HCID 57556173 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | (8-Methyl-2-o-tolylquinolin-3-yl)methanamine | HCID 57707793 | — |
Reaction Steps
Prepared according to Procedure D using 3-(chloromethyl)-8-methyl-2-o-tolyl-quinoline (667 mg, 2.4 mmol) in DMSO (10 mL) was added NaN3 (500 mg, 3 eq). After purification, (8-methyl-2-o-tolylquinolin-3-yl)methanamine was obtained as pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08586739B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-d97d695861aa4378852fafc4e44ccfbb |
| Source note | uspto-grants-2013_11 |