Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 2-Bromothiazole | HCID 76430 | — |
| Reactant | Methyl isonipecotate | HCID 424914 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 60658785 | HCID 60658785 | — |
Reaction Steps
A mixture of methyl piperidine-4-carboxylate (2.045 g), 2-bromothiazole (1.64 g), and Cs2CO3 (5.86 g) in N,N-dimethylformamide (15 mL) was heated at 100° C. overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08586754B2 |
|---|
| Source dataset | uspto-grants-2013_11 |
|---|
| ORD ID | ord-484fd5b1b70f478a8a33793ed0ae4738 |
|---|
| Source note | uspto-grants-2013_11 |
|---|
