HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → HCID 57617105, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | Ethyl 3-[(4-bromo-3-methoxyphenyl)amino]-3-phenylacrylate | HCID 58005168 | — |
| Solvent | 1,1'-Biphenyl, mixt. with 1,1'-oxybis(benzene) | HCID 24670 | — |
| Product | HCID 57617105 | HCID 57617105 | 88.5% |
Reaction Steps
DOWTHERM A (450 mL) was heated to reflux (˜300 C). A mixture of the product from step 2 (49 g, 130 mmol) in DOWTHERM A (50 mL) was added to the heated DOWTHERM A solution portionwise. The mixture was stirred at reflux for 30 min after the addition was complete. The mixture was cooled RT, and hexane (400 mL) was added. The mixture was stirred for 30 min and filtered, and the solids were washed with hexane to give the title compound (38 g, 88% yield). LRMS (M+H)+ Calcd.: 330.0; found 330.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08591878B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-d0bbaba9470b47b2b146dfb92ba4ccee |
| Source note | uspto-grants-2013_11 |