HRID2046188

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11053463

tert-Butyl (4S)-4-(hydroxymethyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate

C11H21NO4

结构：CCOC(=O)c1cc(COc2ccccc2)nn1C[C@@H]1COC(C)(C)N1C(=O)OC(C)(C)C

HCID70654332

未命名化合物

HCID178469067

未命名化合物

PRODUCTS

生成物

HCID70654325

未命名化合物

PROCEDURE

实验过程

The compound was prepared from 5-phenoxymethyl-2H-pyrazole-3-carboxylic acid ethyl ester and (S)-1-boc-2,2-dimethyl-4-hydroxymethyl-oxazolidine using the method described in the preceding example 29 (R)-4-(5-ethoxycarbonyl-3-phenoxymethyl-pyrazol-1-ylmethyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e1cfb0ccc921469891d6216e972cffe1
来源数据集: uspto-grants-2013_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08592422B2
来源说明: uspto-grants-2013_11

反应 SMILES

C(OC(C1NN=C(COC2C=CC=CC=2)C=1)=O)C.CC1(C)OC[C@H](CO)N1C(OC(C)(C)C)=O.[C:35]([O:39][C:40]([N:42]1[C@H:46]([CH2:47][N:48]2[C:52]([C:53]([O:55][CH2:56][CH3:57])=[O:54])=[CH:51][C:50]([CH2:58][O:59][C:60]3[CH:65]=[CH:64][CH:63]=[CH:62][CH:61]=3)=[N:49]2)[CH2:45][O:44][C:43]1([CH3:67])[CH3:66])=[O:41])([CH3:38])([CH3:37])[CH3:36]>>[C:35]([O:39][C:40]([N:42]1[C@@H:46]([CH2:47][N:48]2[C:52]([C:53]([O:55][CH2:56][CH3:57])=[O:54])=[CH:51][C:50]([CH2:58][O:59][C:60]3[CH:61]=[CH:62][CH:63]=[CH:64][CH:65]=3)=[N:49]2)[CH2:45][O:44][C:43]1([CH3:66])[CH3:67])=[O:41])([CH3:36])([CH3:37])[CH3:38]