HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloropyridine → 5-(4-Methoxy-benzyl)-2-(pyridin-2-yloxymethyl)-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloropyridine | HCID 7977 | — |
| Reactant | 5-(4-fluorophenyl)-2-(pyridin-2-yloxymethyl)-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one | HCID 67973779 | — |
| Reactant | 2-Hydroxymethyl-5-(4-methoxy-benzyl)-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one | HCID 67974437 | — |
| Product | 5-(4-Methoxy-benzyl)-2-(pyridin-2-yloxymethyl)-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one | HCID 67974610 | — |
Reaction Steps
The compound was prepared from 2-hydroxymethyl-5-(4-methoxy-benzyl)-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one and 2-chloropyridine using the method described in the preceding example 53 (5-(4-fluoro-phenyl)-2-(pyridin-2-yloxymethyl)-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-4-one).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08592422B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-71bf684193d84cfc80cdcf6d3f6eecdb |
| Source note | uspto-grants-2013_11 |