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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2046351Generated: October 25, 2026

1-Benzyl-N-cyclopropylpiperidin-4-amine → Tert-butyl 2-(2-((1-benzylpiperidine-4-yl)(cyclopropyl)amino)-2-oxoethoxy)-4,6-dimethylpyrimidine-5-ylcarbamate

https://huagongshe.com/reaction/2046351

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Benzyl-N-cyclopropylpiperidin-4-amineHCID 2735481—
Reactant2-(5-(Tert-butoxycarbonylamino)-4,6-dimethylpyrimidine-2-yloxy)acetic acidHCID 59336168—
ProductTert-butyl 2-(2-((1-benzylpiperidine-4-yl)(cyclopropyl)amino)-2-oxoethoxy)-4,6-dimethylpyrimidine-5-ylcarbamateHCID 59336137—

Reaction Steps

The title compound was synthesized from Compound 9 and 1-benzyl-N-cyclopropylpiperidine-4-amine in the same manner as in Example 49.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08592435B2
Source datasetuspto-grants-2013_11
ORD IDord-088140ec1689478ba0079e52f4201c7f
Source noteuspto-grants-2013_11