o-Fluorobenzaldehyde → 4-(2-Fluoro-phenyl)-but-3-en-2-one

HRID 2046440Notes

Reaction equation

[F:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=O.C[O:11][C:12]1[CH:17]=CC=C[C:13]=1C=CC(=O)C>>[F:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH:4]=[CH:13][C:12](=[O:11])[CH3:17]

Participants

Reactant 2

HCID 67970o-Fluorobenzaldehyde

HCID 139181o-Anisalacetone

Product 1

HCID 1374444-(2-Fluoro-phenyl)-but-3-en-2-one

Procedure

The title compound was prepared from 2-fluoro-benzaldehyde (6.2 g, 50.0 mmol), following the procedure describing the synthesis of 4-(2-methoxy-phenyl)-but-3-en-2-one (example 1/a stage 1).

Sources & evidence

ORD record: ord-0fef07c8a20740edad582311e21ae8ff
Source dataset: uspto-grants-2013_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08592430B2

Reaction notes

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