4-(2-Fluoro-phenyl)-but-3-en-2-one → 5-(2-Fluorophenyl)cyclohexane-1,3-dione

HRID 2046441Notes

Reaction equation

HRID 2046441 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10](=[O:12])[CH3:11].C[O:14][C:15]1C=CC=C[C:16]=1C1CC(=O)CC(=O)C1>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]1[CH2:16][C:15](=[O:14])[CH2:11][C:10](=[O:12])[CH2:9]1

Participants

3

Reactant 2

HCID 1374444-(2-Fluoro-phenyl)-but-3-en-2-oneHCID 171223135-(2-Methoxyphenyl)-1,3-cyclohexanedione

Product 1

HCID 136448415-(2-Fluorophenyl)cyclohexane-1,3-dione

Procedure

The title compound was prepared from 4-(2-fluoro-phenyl)-but-3-en-2-one (7.3 g, 44.5 mmol), stage 1, following the procedure describing the synthesis of 5-(2-methoxy-phenyl)-cyclohexane-1,3-dione (example 1/a stage 2).

Sources & evidence

ORD record
ord-2898411d909d4eec958fa43b4069f07b
Source dataset
uspto-grants-2013_11
Patent number
US08592430B2

Reaction notes

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