3-Fluorobenzaldehyde → 4-(3-Fluoro-phenyl)-but-3-en-2-one

HRID 2046444Notes

Reaction equation

HRID 2046444 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH:5]=O.C[O:11][C:12]1[CH:17]=CC=C[C:13]=1C=CC(=O)C>>[F:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:13][C:12](=[O:11])[CH3:17])[CH:7]=[CH:8][CH:9]=1

Participants

3

Reactant 2

HCID 680093-FluorobenzaldehydeHCID 139181o-Anisalacetone

Product 1

HCID 666910324-(3-Fluoro-phenyl)-but-3-en-2-one

Procedure

The title compound was prepared from 3-fluoro-benzaldehyde (4.8 g, 40.0 mmol), following the procedure describing the synthesis of 4-(2-methoxy-phenyl)-but-3-en-2-one (example 1/a stage 1).

Sources & evidence

ORD record
ord-8101a802151a4651a2e41f376baa01d0
Source dataset
uspto-grants-2013_11
Patent number
US08592430B2

Reaction notes

Loading…