5-(2-Methoxyphenyl)-1,3-cyclohexanedione → HCID 53406894, compound

HRID 2046449Notes

Reaction equation

HRID 2046449 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[CH:9]=[CH:10][C:11](=[O:13])[CH3:12].C[O:15][C:16]1C=CC=C[C:17]=1C1CC(=O)CC(=O)C1>>[Br:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[CH:9]1[CH2:17][C:16](=[O:15])[CH2:12][C:11](=[O:13])[CH2:10]1

Participants

3

Reactant 2

HCID 171223135-(2-Methoxyphenyl)-1,3-cyclohexanedioneHCID 67065312HCID 67065312, compound

Product 1

HCID 53406894HCID 53406894, compound

Procedure

The title compound was prepared from 4-(2-bromo-4-fluoro-phenyl)-but-3-en-2-one (34 g, 142 mmol), stage 1, following the procedure describing the synthesis of 5-(2-methoxy-phenyl)-cyclohexane-1,3-dione (example 1/a stage 2).

Sources & evidence

ORD record
ord-4edc772ff68346daba0a2778416ade57
Source dataset
uspto-grants-2013_11
Patent number
US08592430B2

Reaction notes

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