HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2046461Generated: October 26, 2026
Dimethylformamide dimethyl acetal → 2-Dimethylaminomethylene-5-(2-fluoro-phenyl)-cyclohexane-1,3-dione
https://huagongshe.com/reaction/2046461
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | 5-(4-Chlorophenyl)-2-[(dimethylamino)methylene]-1,3-cyclohexanedione | HCID 567070 | — |
| Reactant | 5-(2-Fluorophenyl)cyclohexane-1,3-dione | HCID 13644841 | — |
| Product | 2-Dimethylaminomethylene-5-(2-fluoro-phenyl)-cyclohexane-1,3-dione | HCID 58269402 | — |
Reaction Steps
The title compound was prepared from 5-(2-fluoro-phenyl)-cyclohexane-1,3-dione (1.03 g, 5.0 mmol), example 1/b stage 2, and N,N-dimethylformamide dimethylacetal (5 ml), following the procedure described for the synthesis of 5-(4-chloro-phenyl)-2-dimethylaminomethylene-cyclohexane-1,3-dione (example 2/a stage 1) except that the reaction was stirred at 100° C. for 16 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08592430B2 |
|---|
| Source dataset | uspto-grants-2013_11 |
|---|
| ORD ID | ord-3f6441575ee84caea652a84f86af3523 |
|---|
| Source note | uspto-grants-2013_11 |
|---|
