2-Amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one → 2-Amino-7-(3-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one

Participants

Reaction Steps

The title compound was prepared from 2-acetyl-5-(3-fluoro-phenyl)-cyclohexane-1,3-dione (100 mg, 0.42 mmol), from stage 1, following the procedure describing the synthesis of 2-amino-7-(4-fluoro-phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one (example 3/a stage 2/3) except that the title compound was further purified by recrystallisation in methanol.

Provenance & Evidence