HCID 58269374, compound → HCID 58269416, compound

HRID 2046486Notes

Reaction equation

HRID 2046486 reaction equation
NC1N=CC2C(=O)CC(C3C=CC=CC=3Br)CC=2N=1.[NH2:20][C:21]1[N:30]=[CH:29][C:28]2[C:27](=[O:31])[CH2:26][CH:25]([C:32]3[CH:37]=[CH:36][C:35](F)=[CH:34][C:33]=3[C:39]3[CH:40]=[N:41][CH:42]=[CH:43][CH:44]=3)[CH2:24][C:23]=2[N:22]=1>>[NH2:20][C:21]1[N:30]=[CH:29][C:28]2[C:27](=[O:31])[CH2:26][CH:25]([C:32]3[CH:37]=[CH:36][CH:35]=[CH:34][C:33]=3[C:39]3[CH:40]=[N:41][CH:42]=[CH:43][CH:44]=3)[CH2:24][C:23]=2[N:22]=1

Participants

3

Reactant 2

HCID 58269374HCID 58269374, compoundHCID 58269407HCID 58269407, compound

Product 1

HCID 58269416HCID 58269416, compound

Procedure

The title compound was prepared from 2-amino-7-(2-bromo-phenyl)-7,8-dihydro-6H-quinazolin-5-one (example 2/h stage 2), following the procedure describing the synthesis of 2-amino-7-(4-fluoro-2-pyridin-3-yl-phenyl)-7,8-dihydro-6H-quinazolin-5-one (example 4/a stage 1).

Sources & evidence

ORD record
ord-5c624b77222c4834836311ba77cb898a
Source dataset
uspto-grants-2013_11
Patent number
US08592430B2

Reaction notes

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