HCID 58269395, compound → HCID 76750898, compound

HRID 2046488Notes

Reaction equation

HRID 2046488 reaction equation
[NH2:1][C:2]1[N:11]=[CH:10][C:9]2[C:8](=O)[CH2:7][CH:6]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[C:19]3[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=3)[CH2:5][C:4]=2[N:3]=1.NC1N=CC2C(=[N:36][OH:37])CC(C3C=CC(F)=CC=3C3C=NC=CC=3)CC=2N=1>>[NH2:1][C:2]1[N:11]=[CH:10][C:9]2[C:8](=[N:36][OH:37])[CH2:7][CH:6]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=3[C:19]3[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=3)[CH2:5][C:4]=2[N:3]=1

Participants

3

Reactant 2

HCID 58269395HCID 58269395, compoundHCID 76750887HCID 76750887, compound

Product 1

HCID 76750898HCID 76750898, compound

Procedure

The title compound was prepared from 2-amino-7-(2-pyridin-4-yl-phenyl)-7,8-dihydro-6H-quinazolin-5-one from stage 1, following the procedure describing the synthesis of 2-amino-7-(4-fluoro-2-pyridin-3-yl-phenyl)-7,8-dihydro-6H-quinazolin-5-one oxime (example 4/a stage 2).

Sources & evidence

ORD record
ord-9bd2fc10adc54b8ba666d3ace546b1bf
Source dataset
uspto-grants-2013_11
Patent number
US08592430B2

Reaction notes

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