HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2,2,2-Trifluoroacetamido)cyclopropane-1-carboxylic acid → 1-(2,2,2-Trifluoro-acetylamino)-cyclopropanecarboxylic acid ((rac)-3-bromo-6,7-dihydro-5H-[1]pyrindin-7-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2,2,2-Trifluoroacetamido)cyclopropane-1-carboxylic acid | HCID 12988800 | — |
| Reactant | 3-Bromo-6,7-dihydro-5H-cyclopenta[B]pyridin-7-amine | HCID 71217263 | — |
| Product | 1-(2,2,2-Trifluoro-acetylamino)-cyclopropanecarboxylic acid ((rac)-3-bromo-6,7-dihydro-5H-[1]pyrindin-7-yl)-amide | HCID 89391511 | — |
Reaction Steps
In analogy to the procedure described for the preparation of intermediate A-1 [B], (rac)-3-bromo-6,7-dihydro-5H-[1]pyrindin-7-ylamine has been coupled with 1-(2,2,2-trifluoroacetamido)cyclopropanecarboxylic acid (intermediate A-1 [A]) to yield the title compound as grey solid. MS: 392.0 (MH+, 1Br).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08592426B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-ad3fd3f151f547e5b9bcf3a18b8c7b55 |
| Source note | uspto-grants-2013_11 |