Pyridazine-4-carboxylic Acid → Pyridazine-4-carboxylic acid(1-{(rac) 3-[5-chloro-3-fluoro-2-(5-methyl-[1,2,4]oxadiazol-3-yl)-phenyl]-6,7-dihydro-5H-[1]pyrindin-7-ylcarbamoyl}-cyclopropyl)-amide

Participants

Reaction Steps

In analogy to the procedure described for the preparation of intermediate A-1 [B], 1-amino-cyclopropanecarboxylic acid{(rac)-3-[5-chloro-3-fluoro-2-(5-methyl-[1,2,4]oxadiazol-3-yl)-phenyl]-6,7-dihydro-5H-[1]pyrindin-7-yl}-amide (example 37) has been coupled with pyridazine-4-carboxylic acid to yield the title compound as light brown amorphous solid. MS: 534.1 (MH+, 1Cl).

Provenance & Evidence