HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Carbonate → HCID 68602292, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Carbonate | HCID 11125 | — |
| Reactant | (2S,3S)-3-(1-hydroxy-1-methylethyl)-2-methylpyrrolidine | HCID 55299039 | — |
| Reactant | 2-Chloro-4-fluoro-5-methylbenzonitrile | HCID 56965563 | — |
| Product | HCID 68602292 | HCID 68602292 | — |
Reaction Steps
Using 2-chloro-4-fluoro-5-methylbenzonitrile (848 mg), (2S,3S)-3-(1-hydroxy-1-methylethyl)-2-methylpyrrolidine 1/2 oxalate (1.04 g) and lithium carbonate (784 mg, 10.6 mmol), the title compound was obtained as a colorless solid (yield: 590 mg) by an operation similar to that in Example 3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08592452B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-1c354ebd061d47048118f0c2833ea03e |
| Source note | uspto-grants-2013_11 |