HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dichloro-4-fluorobenzonitrile → HCID 59370509, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dichloro-4-fluorobenzonitrile | HCID 22378515 | — |
| Reactant | HCID 54198127 | HCID 54198127 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | Lithium Carbonate | HCID 11125 | — |
| Product | HCID 59370509 | HCID 59370509 | — |
Reaction Steps
Using 2,3-dichloro-4-fluorobenzonitrile (400.5 mg), 0.9 mol/L solution (2.35 mL) of (2S,3S)-2-methylpyrrolidin-3-ol in dimethyl sulfoxide and lithium carbonate (78 mg), the title compound was obtained as yellow crystals (yield: 417 mg) by an operation similar to that in Example 3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08592452B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-af9ead7cdefb45b7b584e91bac71c226 |
| Source note | uspto-grants-2013_11 |