Methyl iodide → 4-[4-(Azetidine-1-carbonyl)-3-fluoro-phenoxy]-2-methoxymethyl-2-methyl-2,3-dihydro-benzofuran-6-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([O:2][C:3]([c:4]1[cH:5][c:6]([O:7][c:8]2[cH:9][cH:10][c:11]([S:12]([CH3:13])(=[O:14])=[O:15])[cH:16][cH:17]2)[c:18]2[c:25]([cH:26]1)[O:24][CH:20]([CH2:21][O:22][CH3:23])[CH2:19]2)=[O:27])([CH3:28])([CH3:29])[CH3:30].[C:31]([CH3:32])([CH3:33])([CH3:34])[O:35][C:36](=[O:37])[c:38]1[cH:39][c:40]2[c:41]([c:48]([O:50][c:51]3[cH:52][c:53]([F:63])[c:54]([C:57](=[O:58])[N:59]4[CH2:60][CH2:61][CH2:62]4)[cH:55][cH:56]3)[cH:49]1)[CH2:42][C:43]([CH3:45])([CH2:46][OH:47])[O:44]2.[CH3:64][I:65]>>[CH3:1][O:47][CH2:46][C:43]1([CH3:45])[CH2:42][c:41]2[c:40]([cH:39][c:38]([C:36]([O:35][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:37])[cH:49][c:48]2[O:50][c:51]2[cH:52][c:53]([F:63])[c:54]([C:57](=[O:58])[N:59]3[CH2:60][CH2:61][CH2:62]3)[cH:55][cH:56]2)[O:44]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-65e79d62be254461a586fc629cac3a33
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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