HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Bromopyridine-2-carboxylic acid → HCID 53223369, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Bromopyridine-2-carboxylic acid | HCID 593919 | — |
| Reactant | 2-Fluoro-5-methoxyphenylboronic acid | HCID 4157211 | — |
| Catalyst | HCID 178418807 | HCID 178418807 | — |
| Product | HCID 53223369 | HCID 53223369 | 95% |
Reaction Steps
Method 1 was followed using 6-bromopicolinic acid (1.0 equiv.) and 2-fluoro-5-methoxyphenylboronic acid (1.3 equiv.) and Pd(dppf)Cl2-DCM (0.15 equiv.) to give 6-(2-fluoro-5-methoxyphenyl)picolinic acid in 95% yield. LC/MS=248.2 (M+H), Rt=0.78 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08592455B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-f3496dfdc62742f49cb444d72617dd75 |
| Source note | uspto-grants-2013_11 |