HRID2046946

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C[C@H](c1c(Cl)ccc(F)c1Cl)c1c[nH]c2ncc(Br)cc12

HCID58431445

未命名化合物

结构：COC(=O)C(C)(C)n1cc(B2OC(C)(C)C(C)(C)O2)cn1

HCID59599416

未命名化合物

PRODUCTS

生成物

结构：COC(=O)C(C)(C)n1cc(-c2cnc3[nH]cc([C@H](C)c4c(Cl)ccc(F)c4Cl)c3c2)cn1

HCID67362909

未命名化合物

PROCEDURE

实验过程

The 2-(4-{3-[(S)-1-(2,6-Dichloro-3-fluorophenyl)ethyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}-pyrazol-1-yl)-2-methylpropionic acid methyl ester was prepared from 5-bromo-3-[(S)-1-(2,6-dichloro-3-fluorophenyl)ethyl]-1H-pyrrolo[2,3-b]pyridine and 2-methyl-2-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)pyrazol-1-yl]propionic acid methyl ester as described in Example 60.