Methyl iodide → HCID 178503516, compound

Participants

Reaction Conditions

Reaction Steps

4-hydroxy-6-mercapto-3-methylpyrazolo[3,4-d]pyrimidine (14 g) was dissolved in a solution of 10 g. of sodium hydroxide in 300 ml. of water. The solution was cooled to 5° C. and shaken with 12 g. of methyl iodide. After 15-20 minutes, the solution was charcoaled, filtered and acidified with acetic acid to yield 12 g. of crude product. Recrystallization in acidic acid gave the product. MS (ES+): 197.0 (M+1)+.

Provenance & Evidence