4-Chlorobutyldimethylphosphine oxide → [4-(1,3-Dimethylxanthin-7-yl)butyl]dimethylphosphine Oxide

HRID 2047Notes

Reaction equation

HRID 2047 reaction equation
[Na].[CH3:2][N:3]1[C:12](=[O:13])[C:11]2[NH:10][CH:9]=[N:8][C:7]=2[N:6]([CH3:14])[C:4]1=[O:5].Cl[CH2:16][CH2:17][CH2:18][CH2:19][P:20](=[O:23])([CH3:22])[CH3:21]>>[CH3:2][N:3]1[C:12](=[O:13])[C:11]2[N:10]([CH2:16][CH2:17][CH2:18][CH2:19][P:20](=[O:23])([CH3:22])[CH3:21])[CH:9]=[N:8][C:7]=2[N:6]([CH3:14])[C:4]1=[O:5]

Participants

3

Reactant 2

HCID 196891574-Chlorobutyldimethylphosphine oxideHCID 669736033,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione, sodium salt

Product 1

HCID 19689134[4-(1,3-Dimethylxanthin-7-yl)butyl]dimethylphosphine Oxide

Procedure

The title substance was prepared from 10.1 g (0.05 mol) of 1,3-dimethyl-xanthine sodium salt and 4-chlorobutyldimethylphosphine oxide analogously to Example 63.

Sources & evidence

ORD record
ord-7999045b166a4c6fb3a5b43a4772dfa0
Source dataset
uspto-grants-1998_03
Patent number
US05728686

Reaction notes

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