Ethyl 3-oxocyclopentanecarboxylate → Ethyl 1,4-dioxaspiro[4.4]nonane-7-carboxylate

HRID 2047082Notes

Reaction equation

HRID 2047082 reaction equation
[O:1]1[C:5]2([CH2:10][CH2:9][CH:8]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH2:7]C2)[O:4][CH2:3][CH2:2]1.O=C1CCC(C(OCC)=O)C1.O=C1CCC(C(OCC)=O)CC1>>[O:4]1[C:5]2([CH2:10][CH2:9][CH:8]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH2:7]2)[O:1][CH2:2][CH2:3]1

Participants

4

Reactant 3

HCID 223136Ethyl 3-oxocyclopentanecarboxylateHCID 317638Ethyl 4-oxocyclohexanecarboxylateHCID 10488810Ethyl 1,4-dioxaspiro(4.5)decane-8-carboxylate

Product 1

HCID 245433Ethyl 1,4-dioxaspiro[4.4]nonane-7-carboxylate

Procedure

Ethyl 1,4-dioxaspiro[4.4]nonane-7-carboxylate was synthesized in a manner similar to the synthesis of ethyl 1,4-dioxaspiro[4.5]decane-8-carboxylate, but with ethyl 3-oxocyclopentanecarboxylate substituted for ethyl 4-oxocyclohexanecarboxylate.

Sources & evidence

ORD record
ord-a8de9d7074194e77bd721e8337559542
Source dataset
uspto-grants-2013_11
Patent number
US08591943B2

Reaction notes

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