HCID 67494607, compound → HCID 66733702, compound

Participants

Reaction Steps

A mixture of (R)-5-(1-(5-(1-(benzyloxy)ethyl)-1,3,4-oxadiazol-2-yl)piperidin-4-yl)-3-(6-phenylpyridin-3-yl)-N,N-bis((2-(trimethylsilyl)ethoxy)methyl)pyrazolo[1,5-a]pyrimidin-7-amine (105 mg), 20% Pd(OH)2/C (150 mg) in MeOH (4 mL) was stirred under hydrogen (60 psi) overnight. After filtration, washing with EtOAc 4 times and concentration in vacuo the residue was purified on silica gel. Elution with EtOAc/Hexanes (0-100%) gave the title compound (32 mg, 43%).

Provenance & Evidence