HuagongsheHuagongshe Chemistry Print Report · For research reference only
(5R)-5-[(1S,2S)-1-Benzyloxy-3-(3-benzyloxy-5-fluoro-phenyl)-2-dibenzylamino-propyl]-2-hydroxy-morpholine-4-carboxylic acid tert-butyl ester → HCID 68562782, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (5R)-5-[(1S,2S)-1-Benzyloxy-3-(3-benzyloxy-5-fluoro-phenyl)-2-dibenzylamino-propyl]-2-hydroxy-morpholine-4-carboxylic acid tert-butyl ester | HCID 68563622 | — |
| Reactant | Trifluoromethanesulfonic acid 2-fluoro-1-fluoromethyl-1-methyl-ethyl ester | HCID 86615366 | — |
| Product | HCID 68562782 | HCID 68562782 | — |
Reaction Steps
Beginning with (5R)-5-[(1S,2S)-1-Benzyloxy-3-(3-benzyloxy-5-fluoro-phenyl)-2-dibenzylamino-propyl]-2-hydroxy-morpholine-4-carboxylic acid tert-butyl ester and trifluoromethanesulfonic acid 2-fluoro-1-fluoromethyl-1-methyl-ethyl ester, the desired compound may be prepared essentially as described in Preparation 306.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745438B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-915a0a8e6e79446a8758cc829ccf91e4 |
| Source note | uspto-grants-2010_06 |